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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03039] Immunology neurotensin

SKU: 1056920565

4.7
EUR111.00 EUR135.00

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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03039] Immunology neurotensinERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

neurotensin

which has many cysteine residues with conserved spacing

making it possible to observe cells clearly under light microscopes and fluorescence microscopes

Inhibition of this protein's activity may confer anticancer benefits

It is encoded by the single ACHE gene

ErbB-3 Polyclonal Antibody, 20ul[BT-AP03039] Immunology neurotensinERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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