IKK Gamma Polyclonal Antibody, 100ul[BT-AP04426] Liquid Handling ＆Storage • Offer a wide range

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AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH| MIM 113508) when phosphorylated (Kovacina et al

Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain

Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation

The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation

IKK Gamma Polyclonal Antibody, 100ul[BT-AP04426] Liquid Handling ＆Storage • Offer a wide rangeIKBKG encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.