Frizzled-10 Polyclonal Antibody, 50ul[BT-AP03355] Cell Proliferation The protein encoded is a

The protein encoded is a member of the PI3/PI4-kinase family

a region associated with Cornelia de Lange syndrome

This protein can interact with the check point protein RAD1 but not with RAD9

Several splice variants encoding different isoforms have been found for this gene

subcellular location:Also present in PML nuclear bodies

Frizzled-10 Polyclonal Antibody, 50ul[BT-AP03355] Cell Proliferation The protein encoded is aFZD10 is a member of the frizzled gene family. Members of this family encode 7 transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up regulated in two cases of primary colon cancer.