p53 Polyclonal Antibody, 50ul[BT-AP06821] Cryogenic Vials FOXO1 belongs to the forkhead

FOXO1 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain

which is found mainly in the cytoplasm

A pseudogene of this gene is found on chromosome 9

but it has been mapped to 4q

The encoded WD-repeat protein may be involved in microtubule formation

p53 Polyclonal Antibody, 50ul[BT-AP06821] Cryogenic Vials FOXO1 belongs to the forkheadTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni