Insulin R Polyclonal Antibody, 50ul[BT-AP04565] Cell Senescence Inhibitor of PPP1CA

Inhibitor of PPP1CA

Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

NOL3 encodes an anti-apoptotic protein nucleolar protein 3 that has been shown to down-regulate the enzyme activities of caspase 2

a severe intrahepatic cholestasis that results in transient neonatal jaundice

Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies

Insulin R Polyclonal Antibody, 50ul[BT-AP04565] Cell Senescence Inhibitor of PPP1CAINSR encodes a member of the receptor tyrosine kinase family of proteins. Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited