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RNF41 Polyclonal Antibody, 20ul Immunology This gene is a member

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RNF41 Polyclonal Antibody, 20ul Immunology This gene is a memberThis gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2 associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants.

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Description

This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE)

It has been shown to be involved in diverse biological processes

The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid glands

Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation

The protein encoded by this gene is similar to the chicken and mouse CRTAP genes

RNF41 Polyclonal Antibody, 20ul Immunology This gene is a memberThis gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2 associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants.

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