MBP Monoclonal Antibody, 100ul Cryogenic Vials Knockout studies of the mouse

Knockout studies of the mouse homolog suggest RAD50 is essential for cell growth and viability

IRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase

Expression of this gene has been found to be upregulated in small cell lung cancers

The Transcription factor 4 recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers

is also involved in interaction with KSR1 and may regulate its localization and stability

MBP Monoclonal Antibody, 100ul Cryogenic Vials Knockout studies of the mouseThis gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified.