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NAB2 Polyclonal Antibody, 50ul Primary Antibodies The protein encoded by this

SKU: 20546508797

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NAB2 Polyclonal Antibody, 50ul Primary Antibodies The protein encoded by thisNAB2 encodes a member of the family of NGFI A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo or hetero multimerize with other EGR or NAB proteins through a conserved N terminal domain, and repress transcription through two partially redundant C terminal domains. Transcriptional repression by the encoded protein is

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Description

The protein encoded by this gene is a transcription factor of the PR-domain protein family

and may also have a role in controlling cell growth and/or differentiation

cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs)

Evidence suggests that this protein also protects a small subset of cohesin found along the length of the chromosome arms during mitotic prophase

Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha

NAB2 Polyclonal Antibody, 50ul Primary Antibodies The protein encoded by thisNAB2 encodes a member of the family of NGFI A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo or hetero multimerize with other EGR or NAB proteins through a conserved N terminal domain, and repress transcription through two partially redundant C terminal domains. Transcriptional repression by the encoded protein is

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