GBLP Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) TUSC5 (tumor suppressor candidate 5)

TUSC5 (tumor suppressor candidate 5)

Mutations in this gene are associated with acromesomelic dysplasia

Several alternatively spliced transcript variants encoding different isoforms have been described for this gene

and cancer growth and metastasis

The protein (BUB1 mitotic checkpoint serine/threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C)

GBLP Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) TUSC5 (tumor suppressor candidate 5)The WD repeats domain 5 mediates interaction with TRIM63.,Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. May be involved in up regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, serves as a platform for SRC activation or inactivation. May play an important role in the developing brain and neuronal differentiation.,Belongs to the WD