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GSK3Beta mouse Monoclonal Antibody(1A6), 50ul Adenovirus Packaging and it apparently protects neurons

SKU: 22043300136

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GSK3Beta mouse Monoclonal Antibody(1A6), 50ul Adenovirus Packaging and it apparently protects neuronsThe protein encoded by this gene is a serine threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants

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Description

and it apparently protects neurons against oxidative stress and cell death

The proteasome-mediated process ensures the production of both p50 and p105 and preserves their independent function| although processing of NFKB1/p105 also appears to occur post-translationally

It plays a role in the regulation of signal transduction cascades| contributing to both cell proliferation and survival| and provides a selective advantage in tumorigenesis

It heteromultimerizes with another MAGUK protein

which include cyclin A

GSK3Beta mouse Monoclonal Antibody(1A6), 50ul Adenovirus Packaging and it apparently protects neuronsThe protein encoded by this gene is a serine threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants

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