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POLR3B Polyclonal Antibody, 100ul Capsule Filter DVL3 is a member of

SKU: 22223301169

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POLR3B Polyclonal Antibody, 100ul Capsule Filter DVL3 is a member ofPOLR3B (RNA polymerase III subunit B) encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for POLR3B.

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Description

DVL3 is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene

Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene| and a pseudogene of this gene is located on the long arm of chromosome 19

Polymorphisms in this gene may be associated with susceptibility for migraine headaches

This protein can bind to cells derived from T- and B-lymphocytes

Three transcript variants encoding two different proteins have been found for CSNK2A1

POLR3B Polyclonal Antibody, 100ul Capsule Filter DVL3 is a member ofPOLR3B (RNA polymerase III subunit B) encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for POLR3B.

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