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Neu Polyclonal Antibody, 50ul[BT-AP05908] Antibody Development This gene is mapped to

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Neu Polyclonal Antibody, 50ul[BT-AP05908] Antibody Development This gene is mapped toERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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Description

This gene is mapped to the MHC region on chromosome 6p21

The UBP domain of USP13 contains a catalytic site

Additional functions associated with the protein include endocytic recycling of occludin

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis

Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein

Neu Polyclonal Antibody, 50ul[BT-AP05908] Antibody Development This gene is mapped toERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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