p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences Mutations in this gene are

Mutations in this gene are associated with erythrocytosis familial type 4

T-cell acute lymphoblastic leukemia

UBCE7IP1 isoform 3 (ZIN)

The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM

which consists of 2 regions separated by a linker of variable length that folds as a loop

p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences Mutations in this gene areTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni