PAK gamma(Phospho Ser20) Polyclonal Antibody, 20ul Long RNA Synthesis Binding of chemokines to this

Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic

skeletal muscle and heart

Has no enzymatic activity

Finally| this protein binds to the product of the APC gene| which is mutated in adenomatous polyposis of the colon

The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease| the regulation of the cellular response to hypoxia and induction of apoptosis

PAK gamma(Phospho Ser20) Polyclonal Antibody, 20ul Long RNA Synthesis Binding of chemokines to thisThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role