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NCAM-L1 Polyclonal Antibody, 50ul[BT-AP05801] Mammalian Expression MED13 (mediator complex subunit 13)

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NCAM-L1 Polyclonal Antibody, 50ul[BT-AP05801] Mammalian Expression MED13 (mediator complex subunit 13)The protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin like domains and fibronectin like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X

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Description

MED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP

while a translocation event with CXCR4 has been linked with chronic lymphocytic leukemia (CLL)

It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER

Based on similarity to other PPIases| this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

potentially modulating the efficiency of insulin signal transduction

NCAM-L1 Polyclonal Antibody, 50ul[BT-AP05801] Mammalian Expression MED13 (mediator complex subunit 13)The protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin like domains and fibronectin like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X

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