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DAB2 Rabbit Polyclonal Antibody, 50ul Cellular Cultivation & Health Management Introducing the VT1

SKU: 30793485015

4.6
EUR162.00 EUR192.00

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DAB2 Rabbit Polyclonal Antibody, 50ul Cellular Cultivation & Health Management Introducing the VT1This gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras

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Description

Introducing the VT1

A nonconventional nuclear localization sequence (NLS) has been found for protein kinase cAMP-dependent type I regulatory subunit alpha which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40)

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family

they function in the formation of the right ventricle and aortic arch arteries

progressive sensorineural DFNA44 hearing loss

DAB2 Rabbit Polyclonal Antibody, 50ul Cellular Cultivation & Health Management Introducing the VT1This gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras

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