Shc(Phospho Tyr427) Polyclonal Antibody, 20ul Biomatrix Among its related pathways are

Among its related pathways are Golgi-to-ER retrograde transport and Factors involved in megakaryocyte development and platelet production

Histone deacetylase 4 encoded by HDAC4 belongs to class II of the histone deacetylase/acuc/apha family

The protein functions as a regulator of RNA polymerase II-mediated transcription through elongation and chromatin remodeling functions

Mutations in this gene may be associated with atrial fibrillation

CYP1B1 encodes a member of the cytochrome P450 superfamily of enzymes

Shc(Phospho Tyr427) Polyclonal Antibody, 20ul Biomatrix Among its related pathways areThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.