BRCA1 Polyclonal Antibody, 100ul[BT-AP00965] Sealing Film Mutations in this gene are

Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP)

indicating a potential role for this protein in DNA repair

HATs play important roles in regulating chromatin remodeling

and negatively regulate the function of CDC42

occurring in adolescence or adulthood

BRCA1 Polyclonal Antibody, 100ul[BT-AP00965] Sealing Film Mutations in this gene areBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal