TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets This is supported by studies

This is supported by studies in knockout mice showing development of soft-tissue sarcomas| ovarian stromal cell tumors and a high sensitivity to carcinogenic treatmen

Found in a complex with DNMT3A and HDAC7

The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B

In migrating cells

It is thought that this secreted protein contains antitumor activity

TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets This is supported by studiesAlthough this locus appears to encode a protein similar to trypsinogen the locus is thought to be a transcribed pseudogene. ESTs support its transcription but expression of its predicted protein has not been observed. Its predicted protein sequence differs significantly from the known functional trypsinogens including a different amino acid at the conserved residue 122 which is important for autolysis. This pseudogene and several other trypsinogen