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ERK 1/2 Polyclonal Antibody, 50ul[BT-AP03057] Molecular Weight Markers Mutations in this gene have

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ERK 1/2 Polyclonal Antibody, 50ul[BT-AP03057] Molecular Weight Markers Mutations in this gene haveMAPK1 (mitogen activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon

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Description

Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome| somatic and familial gastrointestinal stromal tumors| and a variety of other cancers

elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system

A missense mutation in RBSN is associated with a defect in the early endocytic pathway

The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis

and to the Ca(2+)/calmodulin-dependent protein kinase subfamily

ERK 1/2 Polyclonal Antibody, 50ul[BT-AP03057] Molecular Weight Markers Mutations in this gene haveMAPK1 (mitogen activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon

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