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p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes 2001 [PubMed 11242035])

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p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes 2001 [PubMed 11242035])TP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

2001 [PubMed 11242035])

Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric

Heavy Chain 4

most notably the t(9|22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR| MIM:151410)

Transcription factor E2F4 encoded by E2F4 is a member of the E2F family of transcription factors

p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes 2001 [PubMed 11242035])TP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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