GPTC8 Polyclonal Antibody, 50ul Molecular Biology The type VII collagen fibril

The type VII collagen fibril

and is involved in muscular excitation and contraction

The protein encoded by this gene is a lymphocyte-expressed ADAM protein

suggesting either heavy glycosylation or dimerization

and Brooke-Spiegler syndrome

GPTC8 Polyclonal Antibody, 50ul Molecular Biology The type VII collagen fibrilThe protein encoded by this gene contains an RNA processing domain, a zinc finger domain, a lysine rich region and a serine rich region. A mutation in the serine rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610). Alternative splicing results in multiple transcript variants encoding different isoforms.