Rat Desmin, DES ELISA Kit, 96T Funnels Three alternatively spliced transcript variants

Three alternatively spliced transcript variants encoding different isoforms have been found for this gene

KRT18 encodes the type I intermediate filament chain keratin 18

They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA| and a second domain which interacts with the rest of the tRNA structure

a GTPase domain

Specific for peptides in the range of 10 to 65 residues

Rat Desmin, DES ELISA Kit, 96T Funnels Three alternatively spliced transcript variantsMuscle specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter connecting the Z disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting