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DOC2A Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries May be involved in macrophage-mediated

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DOC2A Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries May be involved in macrophage-mediatedThere are at least two protein isoforms of the Double C2 protein namely alpha (DOC2A) and beta (DOC2B) which contain two C2 like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC 2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+) dependent neurotransmitter release. Alternative splicing results in multiple transcript variants.

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Description

May be involved in macrophage-mediated cellular proliferation

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter

Multiple IRF7 transcript variants have been identified| although the functional consequences of these have not yet been established

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers

Also found in the heart

DOC2A Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries May be involved in macrophage-mediatedThere are at least two protein isoforms of the Double C2 protein namely alpha (DOC2A) and beta (DOC2B) which contain two C2 like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC 2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+) dependent neurotransmitter release. Alternative splicing results in multiple transcript variants.

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