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LIF Polyclonal Antibody, 50ul Antibody Humanization The protein encoded by this

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LIF Polyclonal Antibody, 50ul Antibody Humanization The protein encoded by thisLeukemia inhibitory factor encoded by LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal fetal interface. Alternatively spliced transcript variants

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Description

The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex

The encoded protein| which is primarily cytosolic but can shuttle to the nucleus| also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer| brain tumors| and lung cancer

Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport

regulating blood pressure

Mutations in this gene have been associated with Krabbe disease| also known as globoid cell leukodystrophy

LIF Polyclonal Antibody, 50ul Antibody Humanization The protein encoded by thisLeukemia inhibitory factor encoded by LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal fetal interface. Alternatively spliced transcript variants

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