FoxO3A Polyclonal Antibody, 100ul[BT-AP15669] General Lab Use This protein may function as

This protein may function as a transcriptional co-activator

These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins

Site-specific binding also suggests that 53BP1 and 53BP2 are involved in p53-mediated tumor suppression

Weakly expressed in kidney

A pseudogene of this gene is found on chromosome 16

FoxO3A Polyclonal Antibody, 100ul[BT-AP15669] General Lab Use This protein may function asThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.