ME2 Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification The conserved amino-terminal domains of

The conserved amino-terminal domains of the four core histones (H2A| H2B| H3| and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs)

This enzyme is localized to the mitochondria and may play a role in programmed cell death

Unlike most ribosomal proteins

This protein is a receptor for members of the epidermal growth factor family

The protein encoded by this gene contains a caspase recruitment domain (CARD)

ME2 Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification The conserved amino-terminal domains ofME2 encodes a mitochondrial NAD dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy.