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DSC1 Rabbit Polyclonal Antibody, 50ul Peptide Modification The protein deficiency in mice

SKU: 42855289360

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DSC1 Rabbit Polyclonal Antibody, 50ul Peptide Modification The protein deficiency in miceThe protein encoded by this gene is a calcium dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members along with the desmogleins are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus a life threatening autoimmune disease is

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Description

The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction

The protein encoded by ROBO2 (roundabout guidance receptor 2) belongs to the ROBO family

Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles

SCN9A (sodium voltage-gated channel alpha subunit 9) encodes a voltage-gated sodium channel which plays a significant role in nociception signaling

enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP

DSC1 Rabbit Polyclonal Antibody, 50ul Peptide Modification The protein deficiency in miceThe protein encoded by this gene is a calcium dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members along with the desmogleins are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus a life threatening autoimmune disease is

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