Histone H3 (Mono Methyl Lys18) Polyclonal Antibody, 50ul Immuno Plates Mutations in this gene are

Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8

|Contains 7 FG-GAP repeats

The protein belongs to the L14E family of ribosomal proteins

The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions

Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis

Histone H3 (Mono Methyl Lys18) Polyclonal Antibody, 50ul Immuno Plates Mutations in this gene areHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin