BM28 Monoclonal Antibody, 50ul[BT-MCA0221] Serum Muckle-Wells syndrome (MWS)

Muckle-Wells syndrome (MWS)

and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency

a multisystem developmental disorder caused by deletion of multiple genes at 7q11

During mouse development Rudhira is expressed in erythropoietic and angiogenic precursors but not in their differentiated progeny

and studies in mice show that overexpression of GSK3B may be relevant to the pathogenesis of Alzheimer disease

BM28 Monoclonal Antibody, 50ul[BT-MCA0221] Serum Muckle-Wells syndrome (MWS)The protein encoded by this gene is one of the highly conserved mini chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6,