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Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression This response is mediated via

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Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression This response is mediated viaThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system

The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation

Keep your experiments running smoothly and confidently without fear of RNA degradation

An important paralog of this gene is UBA52

and the recently identified phosphoprotein PHAX (phosphorylated adaptor for RNA export)

Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression This response is mediated viaThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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