Human Soluble Interleukin 6 Receptor, SIL-6R ELISA Kit, 96T Cell Biology The encoded protein is a

The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases

In cooperation with NOD2 involved in an inflammasome activated by bacterial muramyl dipeptide leading to caspase-1 activation

Generates a C-terminally amidated Peptide

Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (PubMed: 23576617)

In addition to these two main signaling pathways IGF1R signals also through the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT)

Human Soluble Interleukin 6 Receptor, SIL-6R ELISA Kit, 96T Cell Biology The encoded protein is a