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GLI-1 Polyclonal Antibody, 100ul Peptide Library but some of the chains

SKU: 47171973191

4.2
PLN141.00 PLN177.00

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GLI-1 Polyclonal Antibody, 100ul Peptide Library but some of the chainsThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

but some of the chains have been shown to differ with respect to their tissue distribution

UPF1 (UPF1

The BimEL and BimL isoforms may be sequestered to the dynein motor complex through an interaction with the dynein light chain and released from this complex during apoptosis

MAP4 and MAPT/TAU

This protein has been shown to interact with| and inhibit the activity of| TRPS1| a transcription suppressor of GATA-mediated transcription

GLI-1 Polyclonal Antibody, 100ul Peptide Library but some of the chainsThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

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