SH3B4 Polyclonal Antibody, 100ul Liquid Handling ＆Storage Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding different isoforms have been observed

which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases

This protein may function in motility

The transmembrane protein encoded by this gene (interleukin 17A receptor

and are known to be involved in the homologous recombination and repair of DNA

SH3B4 Polyclonal Antibody, 100ul Liquid Handling ＆Storage Two alternatively spliced transcript variantsThis gene encodes a protein with 3 Asn Pro Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo specific control of clathrin mediated endocytosis, specifically controlling the internalization of a specific protein receptor.