NMRL1 Rabbit Polyclonal Antibody, 50ul Enzyme Activity Assays This gene is mapped to

This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK

CDCP1 encodes a transmembrane protein (CUB domain containing protein 1) which contains three extracellular CUB domains and acts as a substrate for Src family kinases

This gene encodes the largest subunit of dynactin

it is also required for poly(A) shortening which is the first step in mRNA decay

Mutations in this gene are the most common cause of Fanconi anemia

NMRL1 Rabbit Polyclonal Antibody, 50ul Enzyme Activity Assays This gene is mapped toThis gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF kappaB in a ubiquitylation dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3 mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants.