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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture The protein may be involved

SKU: 49318005994

4.6
PLN162.00 PLN200.00

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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture The protein may be involvedBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

The protein may be involved in transduction of high-temperature heat responses in sensory ganglia

and is thought to be required for DNA replication from viral origin of replication

Major structural component of the ciliary rootlet

This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides

Phosphorylation at Ser-425 and Ser-428 is required for dissociation from the centrosome at the G2/M boundary

BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture The protein may be involvedBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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