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RBQ-3 Polyclonal Antibody, 100ul Cell Screening and Imaging This gene has multiple pseudogenes

SKU: 49886469484

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RBQ-3 Polyclonal Antibody, 100ul Cell Screening and Imaging This gene has multiple pseudogenesRBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit) encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A binding pocket B. Three alternatively spliced transcript variants

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Description

This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family

In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL)

There are three inhibitory families in the superfamily| including the type 1 cystatins (stefins)| type 2 cystatins and the kininogens

Acts by interacting with the second WW domain of ITCH

The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta)

RBQ-3 Polyclonal Antibody, 100ul Cell Screening and Imaging This gene has multiple pseudogenesRBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit) encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A binding pocket B. Three alternatively spliced transcript variants

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