Smad3 Polyclonal Antibody, 20ul[BT-AP14309] Adeno-associated Virus Packaging The activity of this ubiquitin

The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease| the regulation of the cellular response to hypoxia and induction of apoptosis

This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins

Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN)

Probably involved in formation of autophagosomal vacuoles (autophagosomes)

which is mutated in adenomatous polyposis of the colon

Smad3 Polyclonal Antibody, 20ul[BT-AP14309] Adeno-associated Virus Packaging The activity of this ubiquitinThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of