EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables Three transcript variants encoding two

Three transcript variants encoding two different proteins have been found for this gene

Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms

This gene encodes a protein that is highly similar to the yeast SIN1 protein| a stress-activated protein kinase

This gene also has pseudogenes on chromosomes 9

kidney and heart tissue

EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables Three transcript variants encoding twoEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.