RAD9(Phospho Ser272) Rabbit Polyclonal Antibody, 50ul DNA Oligo Synthesis This gene is a member

This gene is a member of the septin family of nucleotide binding proteins

Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains

where it phosphorylates and inactivates BCKD

Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia

May regulate transepithelial ammonia secretion

RAD9(Phospho Ser272) Rabbit Polyclonal Antibody, 50ul DNA Oligo Synthesis This gene is a memberCatalytic activity: Exonucleolytic cleavage in the 3' to 5' direction to yield nucleoside 5' phosphates. Component of the 9 1 1 cell cycle checkpoint response complex that plays a major role in DNA repair. The 9 1 1 complex is recruited to DNA lesion upon damage by the RAD17 replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long patch base excision repair (LP BER). The 9 1 1