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GPR98 Polyclonal Antibody, 20ul Lentiviral Packaging Alternate allele-specific splice variants

SKU: 52202102425

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GPR98 Polyclonal Antibody, 20ul Lentiviral Packaging Alternate allele-specific splice variantsThis gene encodes a member of the G protein coupled receptor superfamily. The encoded protein contains a 7 transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described.

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Description

Alternate allele-specific splice variants

The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest| and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells

but another polymorphism has been associated with increased plasma cholesterol levels

where most DUF1220 domains are located

Growth factor receptor-bound protein 14 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules

GPR98 Polyclonal Antibody, 20ul Lentiviral Packaging Alternate allele-specific splice variantsThis gene encodes a member of the G protein coupled receptor superfamily. The encoded protein contains a 7 transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described.

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