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dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges Phosphorylated by ATR upon DNA

SKU: 55043811465

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dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges Phosphorylated by ATR upon DNAThymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5 Fluorouracil (5 FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle

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Description

Phosphorylated by ATR upon DNA damage

glycosylated alpha subunit and two smaller beta subunits

This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB)| both anchored in the membrane

MSH6 encodes a member of the DNA mismatch repair MutS family

Suppressor of cytokine signaling 2 encoded by SOCS2 interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling

dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges Phosphorylated by ATR upon DNAThymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5 Fluorouracil (5 FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle

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