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Hrs Polyclonal Antibody, 50ul[BT-AP04215] Metabolic enzymes The product of this gene

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Hrs Polyclonal Antibody, 50ul[BT-AP04215] Metabolic enzymes The product of this geneHepatocyte growth factor regulated tyrosine kinase substrate encoded by HGS regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome dependent degradation.

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Description

The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage

Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP

This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets

IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells

cell-cell signaling

Hrs Polyclonal Antibody, 50ul[BT-AP04215] Metabolic enzymes The product of this geneHepatocyte growth factor regulated tyrosine kinase substrate encoded by HGS regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome dependent degradation.

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