BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos Expression studies in yeast and

Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35

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This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth

Alternate splicing of this gene generates several transcript variants encoding different isoforms

this protein is sometimes secreted

BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos Expression studies in yeast andBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal