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HLA-DOBeta Polyclonal Antibody, 50ul Variant Libraries (PMID: 20173098 ) From BLAST

SKU: 57890739490

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HLA-DOBeta Polyclonal Antibody, 50ul Variant Libraries (PMID: 20173098 ) From BLASTHLA DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28

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Description

(PMID: 20173098 ) From BLAST result

2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits

which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis

MAN1B1 encodes an enzyme belonging to the glycosyl hydrolase 47 family

HLA-DOBeta Polyclonal Antibody, 50ul Variant Libraries (PMID: 20173098 ) From BLASTHLA DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28

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