JAM3 Polyclonal Antibody, 20ul 3D Cell Culture Consumables Interleukin-1 receptor-associated kinase 3 is

Interleukin-1 receptor-associated kinase 3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling

Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546| 20937277)

A pseudogene exists on chromosome 18

induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins

A pseudogene corresponding to MRPS18A is found on chromosome 3p

JAM3 Polyclonal Antibody, 20ul 3D Cell Culture Consumables Interleukin-1 receptor-associated kinase 3 isTight junctions represent one mode of cell to cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable