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GTSE1 Polyclonal Antibody, 20ul sgRNA Oligos PNPLA6 encodes a phospholipase that

SKU: 60745537477

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GTSE1 Polyclonal Antibody, 20ul sgRNA Oligos PNPLA6 encodes a phospholipase thatThe protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

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Description

PNPLA6 encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine

chemotaxis

High levels of expression of this gene have been observed in several B cell-derived lymphomas

The encoded protein functions as either a homodimer or as a heterodimer with similar family members

Their cellular concentrations are regulated by the encoded protein

GTSE1 Polyclonal Antibody, 20ul sgRNA Oligos PNPLA6 encodes a phospholipase thatThe protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

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