SPTA1 Rabbit Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Alternative splicing results in multiple

Alternative splicing results in multiple transcript variants encoding distinct proteins

In their unbound form

Down-regulated in immortalized fibroblasts isolated after a proliferative crisis accompanied with massive cell death

the ortholog of this gene is expressed in the cerebral cortex

This gene belongs to the G-protein coupled receptor 1 family

SPTA1 Rabbit Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Alternative splicing results in multipleSpectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape arrangement of transmembrane proteins and organization of organelles. It is a tetramer made up of alpha beta dimers linked in a head to head arrangement. This gene is one member of a family of alpha spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats