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FAST Polyclonal Antibody, 50ul Contamination Detection & Removal The encoded protein may interact

SKU: 61587285895

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FAST Polyclonal Antibody, 50ul Contamination Detection & Removal The encoded protein may interactFas activated serine threonine kinase encoded by FASTK is a member of the serine threonine protein kinase family. This kinase was shown to be activated rapidly during Fas mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis promoting nuclear RNA binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found

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Description

The encoded protein may interact with other cell cycle regulators

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family

Mutations in this gene cause Schwartz-Jampel syndrome type 2

which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes

and anal leukoplakia

FAST Polyclonal Antibody, 50ul Contamination Detection & Removal The encoded protein may interactFas activated serine threonine kinase encoded by FASTK is a member of the serine threonine protein kinase family. This kinase was shown to be activated rapidly during Fas mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis promoting nuclear RNA binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found

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