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AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis The protein encoded by this

SKU: 62385108741

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AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis The protein encoded by thisAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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Description

The protein encoded by this gene is involved in processes including neurite growth and migration

EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins

neurotransmitter phenotype

which are involved in microtubule assembly and important for neurogenesis

Tyrosine phosphorylation seems to occur only at the plasma membrane

AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis The protein encoded by thisAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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